β3-Adrenoreceptor Blockade Reduces Hypoxic Myeloid Leukemic Cells Survival and Chemoresistance

β3-Adrenoreceptor Blockade Reduces Hypoxic Myeloid Leukemic Cells Survival and Chemoresistance

β-adrenergic signaling is known to be involved in cancer progression; in particular, beta3-adrenoreceptor (β3-AR) is associated with different tumor conditions. Currently, there are few data concerning β3-AR in myeloid malignancies. Here, we evaluated β3-AR in myeloid leukemia cell lines and the eff...

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Bibliographic Details
Main Authors: Maura Calvani, Annalisa Dabraio, Gennaro Bruno, Veronica De Gregorio, Marcella Coronnello, Costanza Bogani, Sara Ciullini, Giancarlo la Marca, Marina Vignoli, Paola Chiarugi, Margherita Nardi, Alessandro Maria Vannucchi, Luca Filippi, Claudio Favre
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:International Journal of Molecular Sciences
Subjects:
chemoresistance
myeloid leukemia
β3-adrenoreceptor
Online Access:https://www.mdpi.com/1422-0067/21/12/4210

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