Role of CD8 Regulatory T Cells versus Tc1 and Tc17 Cells in the Development of Human Graft-versus-Host Disease

CD8+ T cells that secrete proinflammatory cytokines play a central role in exacerbation of inflammation; however, a new subpopulation of CD8 regulatory T cells has recently been characterized. This study analyzes the prominent role of these different subpopulations in the development of graft-versus...

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Bibliographic Details
Main Authors: Adriana Gutiérrez-Hoya, Rubén López-Santiago, Jorge Vela-Ojeda, Laura Montiel-Cervantes, Octavio Rodríguez-Cortés, Víctor Rosales-García, Vladimir Paredes-Cervantes, Raúl Flores-Mejía, Daniela Sandoval-Borrego, Martha Moreno-Lafont
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2017/1236219