Colon-specific immune microenvironment regulates cancer progression versus rejection

Colon-specific immune microenvironment regulates cancer progression versus rejection

Immunotherapies have achieved clinical benefit in many types of cancer but remain limited to a subset of patients in colorectal cancer (CRC). Resistance to immunotherapy can be attributed in part to tissue-specific factors constraining antitumor immunity. Thus, a better understanding of how the colo...

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Bibliographic Details
Main Authors: Giulia Trimaglio, Anne-Françoise Tilkin-Mariamé, Virginie Feliu, Françoise Lauzéral-Vizcaino, Marie Tosolini, Carine Valle, Maha Ayyoub, Olivier Neyrolles, Nathalie Vergnolle, Yoann Rombouts, Christel Devaud
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:OncoImmunology
Subjects:
colorectal cancer
immune response polarization
orthotopic model
Online Access:http://dx.doi.org/10.1080/2162402X.2020.1790125

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