The microbiota protects against respiratory infection via GM-CSF signaling
The microbiota promotes resistance to respiratory infection through unclear mechanisms. Here, the authors identify members of the gut and upper airway microbiota that protect against respiratory infection by Streptococcus pneumoniae and Klebsiella pneumoniae by activating GM-CSF signaling.
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| Format: | Article |
| Language: | English |
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Nature Publishing Group
2017-11-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-017-01803-x |
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doaj-42f80173d6014fef9e269abc5d8866a0 |
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Article |
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doaj-42f80173d6014fef9e269abc5d8866a02021-05-11T07:08:01ZengNature Publishing GroupNature Communications2041-17232017-11-018111110.1038/s41467-017-01803-xThe microbiota protects against respiratory infection via GM-CSF signalingRebecca L. Brown0Richard P. Sequeira1Thomas B. Clarke2MRC Centre for Molecular Bacteriology and Infection, Imperial College LondonMRC Centre for Molecular Bacteriology and Infection, Imperial College LondonMRC Centre for Molecular Bacteriology and Infection, Imperial College LondonThe microbiota promotes resistance to respiratory infection through unclear mechanisms. Here, the authors identify members of the gut and upper airway microbiota that protect against respiratory infection by Streptococcus pneumoniae and Klebsiella pneumoniae by activating GM-CSF signaling.https://doi.org/10.1038/s41467-017-01803-x |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Rebecca L. Brown Richard P. Sequeira Thomas B. Clarke |
| spellingShingle |
Rebecca L. Brown Richard P. Sequeira Thomas B. Clarke The microbiota protects against respiratory infection via GM-CSF signaling Nature Communications |
| author_facet |
Rebecca L. Brown Richard P. Sequeira Thomas B. Clarke |
| author_sort |
Rebecca L. Brown |
| title |
The microbiota protects against respiratory infection via GM-CSF signaling |
| title_short |
The microbiota protects against respiratory infection via GM-CSF signaling |
| title_full |
The microbiota protects against respiratory infection via GM-CSF signaling |
| title_fullStr |
The microbiota protects against respiratory infection via GM-CSF signaling |
| title_full_unstemmed |
The microbiota protects against respiratory infection via GM-CSF signaling |
| title_sort |
microbiota protects against respiratory infection via gm-csf signaling |
| publisher |
Nature Publishing Group |
| series |
Nature Communications |
| issn |
2041-1723 |
| publishDate |
2017-11-01 |
| description |
The microbiota promotes resistance to respiratory infection through unclear mechanisms. Here, the authors identify members of the gut and upper airway microbiota that protect against respiratory infection by Streptococcus pneumoniae and Klebsiella pneumoniae by activating GM-CSF signaling. |
| url |
https://doi.org/10.1038/s41467-017-01803-x |
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