Dchs1–Fat4 regulation of polarized cell behaviours during skeletal morphogenesis
How the shape of the sternum is regulated is unclear. Here, the authors identify the Dchs1-Fat4-planar cell polarity pathway as controlling cell orientation and cell intercalation of mesenchymal cells that form skeletal condensations for the mouse sternum, which defines the relative dimensions of th...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2016-05-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms11469 |