A Multivariate Metabolomics Method for Estimating Platelet Mitochondrial Oxygen Consumption Rates in Patients with Sepsis

A Multivariate Metabolomics Method for Estimating Platelet Mitochondrial Oxygen Consumption Rates in Patients with Sepsis

Background: Sepsis-induced alterations in mitochondrial function contribute to organ dysfunction and mortality. Measuring mitochondrial function in vital organs is neither feasible nor practical, highlighting the need for non-invasive approaches. Mitochondrial function may be reflected in the concen...

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Bibliographic Details
Main Authors: Marc R. McCann, Cora E. McHugh, Maggie Kirby, Theodore S. Jennaro, Alan E. Jones, Kathleen A. Stringer, Michael A. Puskarich
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Metabolites
Subjects:
nuclear magnetic resonance spectroscopy
acetylcarnitine
bioenergetics
mitochondrial function
mitochondrial respiration
mitochondria
Online Access:https://www.mdpi.com/2218-1989/10/4/139

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https://www.mdpi.com/2218-1989/10/4/139

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