Comparative study on the independent and combined effects of omega-3 and vitamin B12 on phospholipids and phospholipase A2 as phospholipid hydrolyzing enzymes in PPA-treated rats as a model for autistic traits

Comparative study on the independent and combined effects of omega-3 and vitamin B12 on phospholipids and phospholipase A2 as phospholipid hydrolyzing enzymes in PPA-treated rats as a model for autistic traits

Abstract Background Abnormal phospholipid metabolism is a major component of many neurodevelopmental disorders including autism. Oral administration of propionic acid (PPA) can produce behavioral abnormalities and biochemical features in rodents similar to those observed in autism and can thus be us...

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Bibliographic Details
Main Authors: Hanan Alfawaz, Ramesa Shafi Bhat, Manar Al-Mutairi, Osima M. Alnakhli, Abeer Al-Dbass, Mona AlOnazi, Majidh Al-Mrshoud, Iman H. Hasan, Afaf El-Ansary
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Lipids in Health and Disease
Subjects:
Autism
Propionic acid
Omega-3
Vitamin B12
Phospholipase A2
Phospholipids
Online Access:http://link.springer.com/article/10.1186/s12944-018-0850-1

Internet

http://link.springer.com/article/10.1186/s12944-018-0850-1

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