Molecular interactions between NAFLD and xenobiotic metabolism

Non-alcoholic fatty liver disease (NAFLD), the hepatic manifestation of the metabolic syndrome, is a complex multifactorial disease characterised by metabolic deregulations that include accumulation of lipids in the liver, lipotoxicity and insulin resistance. The progression of NAFLD to NASH and cir...

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Bibliographic Details
Main Authors: Adviti eNaik, Aleš eBelič, Ulrich M Zanger, Damjana eRozman
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-01-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2013.00002/full