RhoA promotes epidermal stem cell proliferation via PKN1-cyclin D1 signaling.

RhoA promotes epidermal stem cell proliferation via PKN1-cyclin D1 signaling.

OBJECTIVE:Epidermal stem cells (ESCs) play a critical role in wound healing, but the mechanism underlying ESC proliferation is not well defined. Here, we explore the effects of RhoA on ESC proliferation and the possible underlying mechanism. METHODS:Human ESCs were enriched by rapid adhesion to coll...

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Bibliographic Details
Main Authors: Fan Wang, Rixing Zhan, Liang Chen, Xia Dai, Wenping Wang, Rui Guo, Xiaoge Li, Zhe Li, Liang Wang, Shupeng Huang, Jie Shen, Shirong Li, Chuan Cao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5319766?pdf=render

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