Multiplex gene analysis reveals T-cell and antibody-mediated rejection-specific upregulation of complement in renal transplants

Abstract In renal transplantation, complement is involved in ischemia reperfusion injury, graft rejection and dysfunction. However, it is still unclear how induction of complement and its activation are initiated. Using allograft biopsies of a well-characterized cohort of 28 renal transplant patient...

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Bibliographic Details
Main Authors: Eva Vonbrunn, Tajana Ries, Stefan Söllner, Janina Müller-Deile, Maike Büttner-Herold, Kerstin Amann, Christoph Daniel
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-94954-3