Characterization of the plant homeodomain (PHD) reader family for their histone tail interactions

Characterization of the plant homeodomain (PHD) reader family for their histone tail interactions

Abstract Background Plant homeodomain (PHD) fingers are central “readers” of histone post-translational modifications (PTMs) with > 100 PHD finger-containing proteins encoded by the human genome. Many of the PHDs studied to date bind to unmodified or methylated states of histone H3 lysine 4 (H3K4...

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Bibliographic Details
Main Authors: Kanishk Jain, Caroline S. Fraser, Matthew R. Marunde, Madison M. Parker, Cari Sagum, Jonathan M. Burg, Nathan Hall, Irina K. Popova, Keli L. Rodriguez, Anup Vaidya, Krzysztof Krajewski, Michael-Christopher Keogh, Mark T. Bedford, Brian D. Strahl
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Epigenetics & Chromatin
Subjects:
Chromatin
Histone methylation
PHD fingers
Histone peptide microarray
Protein domain microarray
Online Access:https://doi.org/10.1186/s13072-020-0328-z

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