T Cells in Gastric Cancer: Friends or Foes

T Cells in Gastric Cancer: Friends or Foes

Gastric cancer is the second cause of cancer-related deaths worldwide. Helicobacter pylori is the major risk factor for gastric cancer. As for any type of cancer, T cells are crucial for recognition and elimination of gastric tumor cells. Unfortunately T cells, instead of protecting from the onset o...

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Main Authors: Amedeo Amedei, Chiara Della Bella, Elena Silvestri, Domenico Prisco, Mario M. D'Elios
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Clinical and Developmental Immunology
Online Access:http://dx.doi.org/10.1155/2012/690571
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spelling doaj-42e0e73d14c546688639eda690e504642020-11-24T22:22:17ZengHindawi LimitedClinical and Developmental Immunology1740-25221740-25302012-01-01201210.1155/2012/690571690571T Cells in Gastric Cancer: Friends or FoesAmedeo Amedei0Chiara Della Bella1Elena Silvestri2Domenico Prisco3Mario M. D'Elios4Patologia Medica, Dipartimento de Biomedicina, Azienda Ospedaliera Universitaria Careggi, Largo Brambilla 3, 50134 Firenze, ItalyPatologia Medica, Dipartimento de Biomedicina, Azienda Ospedaliera Universitaria Careggi, Largo Brambilla 3, 50134 Firenze, ItalyPatologia Medica, Dipartimento de Biomedicina, Azienda Ospedaliera Universitaria Careggi, Largo Brambilla 3, 50134 Firenze, ItalyPatologia Medica, Dipartimento de Biomedicina, Azienda Ospedaliera Universitaria Careggi, Largo Brambilla 3, 50134 Firenze, ItalyPatologia Medica, Dipartimento de Biomedicina, Azienda Ospedaliera Universitaria Careggi, Largo Brambilla 3, 50134 Firenze, ItalyGastric cancer is the second cause of cancer-related deaths worldwide. Helicobacter pylori is the major risk factor for gastric cancer. As for any type of cancer, T cells are crucial for recognition and elimination of gastric tumor cells. Unfortunately T cells, instead of protecting from the onset of cancer, can contribute to oncogenesis. Herein we review the different types, “friend or foe”, of T-cell response in gastric cancer.http://dx.doi.org/10.1155/2012/690571
collection DOAJ
language English
format Article
sources DOAJ
author Amedeo Amedei
Chiara Della Bella
Elena Silvestri
Domenico Prisco
Mario M. D'Elios
spellingShingle Amedeo Amedei
Chiara Della Bella
Elena Silvestri
Domenico Prisco
Mario M. D'Elios
T Cells in Gastric Cancer: Friends or Foes
Clinical and Developmental Immunology
author_facet Amedeo Amedei
Chiara Della Bella
Elena Silvestri
Domenico Prisco
Mario M. D'Elios
author_sort Amedeo Amedei
title T Cells in Gastric Cancer: Friends or Foes
title_short T Cells in Gastric Cancer: Friends or Foes
title_full T Cells in Gastric Cancer: Friends or Foes
title_fullStr T Cells in Gastric Cancer: Friends or Foes
title_full_unstemmed T Cells in Gastric Cancer: Friends or Foes
title_sort t cells in gastric cancer: friends or foes
publisher Hindawi Limited
series Clinical and Developmental Immunology
issn 1740-2522
1740-2530
publishDate 2012-01-01
description Gastric cancer is the second cause of cancer-related deaths worldwide. Helicobacter pylori is the major risk factor for gastric cancer. As for any type of cancer, T cells are crucial for recognition and elimination of gastric tumor cells. Unfortunately T cells, instead of protecting from the onset of cancer, can contribute to oncogenesis. Herein we review the different types, “friend or foe”, of T-cell response in gastric cancer.
url http://dx.doi.org/10.1155/2012/690571
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AT chiaradellabella tcellsingastriccancerfriendsorfoes
AT elenasilvestri tcellsingastriccancerfriendsorfoes
AT domenicoprisco tcellsingastriccancerfriendsorfoes
AT mariomdelios tcellsingastriccancerfriendsorfoes
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