Presence of the <it>CYP2B6 516G> T </it>polymorphism, increased plasma Efavirenz concentrations and early neuropsychiatric side effects in South African HIV-infected patients
<p>Abstract</p> <p>Background</p> <p>The 516G > T polymorphism in exon 4 of the <it>CYP2B6 </it>gene has been associated with increased plasma Efavirenz (EFV) concentrations. EFV concentrations greater than the recommended therapeutic range have been asso...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2010-08-01
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| Series: | AIDS Research and Therapy |
| Online Access: | http://www.aidsrestherapy.com/content/7/1/32 |