The clinical implication of cancer-associated microvasculature and fibroblast in advanced colorectal cancer patients with synchronous or metachronous metastases.

The clinical implication of cancer-associated microvasculature and fibroblast in advanced colorectal cancer patients with synchronous or metachronous metastases.

We aimed to evaluate the clinical significance of microvessel density (MVD), lymphatic vessel density (LVD), and cancer-associated fibroblasts (CAFs) in relation to tumor location in advanced colorectal cancer (CRC).Using immunohistochemistry, we examined 181 advanced CRC patients for CD31 and D2-40...

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Bibliographic Details
Main Authors: Yoonjin Kwak, Hee Eun Lee, Woo Ho Kim, Duck-Woo Kim, Sung-Bum Kang, Hye Seung Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3958375?pdf=render

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