Roles of Nicotinamide Adenine Dinucleotide (NAD+) in Biological Systems

Roles of Nicotinamide Adenine Dinucleotide (NAD+) in Biological Systems

NAD+ has emerged as a crucial element in both bioenergetic and signaling pathways since it acts as a key regulator of cellular and organism homeostasis. NAD+ is a coenzyme in redox reactions, a donor of adenosine diphosphate-ribose (ADPr) moieties in ADP-ribosylation reactions, a substrate for sirtu...

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Bibliographic Details
Main Authors: Palmiro Poltronieri, Nataša Čerekovic
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:Challenges
Subjects:
Nicotinamide adenine dinucleotide (NAD+)
ADP ribose (ADPr)
ADP Ribosyl Transferase (ADPRT)
nicotinamide (Nam)
nicotinamide mononucleotide (NMN)
nicotinamide riboside (NR)
nicotinic acid (NA)
nicotinic acid adenine dinucleotide phosphate (NAADP)
cyclic ADP ribose (cADPr)
post-translational modification (PTM)
deacetylation
poly ADP ribose glycohydrolase (PARG)
Nicotinamide mononucleotide adenylyl transferease (NMNAT-1)
nicotinamide phosphoribosyl transferase (NAMPT)
Online Access:http://www.mdpi.com/2078-1547/9/1/3

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http://www.mdpi.com/2078-1547/9/1/3

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