Microwave-Assisted Regioselective Suzuki Coupling of 2,4-Dichloropyrimidines with Aryl and Heteroaryl Boronic Acids

Microwave-Assisted Regioselective Suzuki Coupling of 2,4-Dichloropyrimidines with Aryl and Heteroaryl Boronic Acids

Suzuki coupling reaction has been often used for the preparation of a diverse set of substituted pyrimidines. In this study, the Suzuki coupling of 2,4-dichloropyrimidines with aryl and heteroaryl boronic acids was investigated. A thorough screening of reaction conditions and the use of microwave ir...

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Bibliographic Details
Main Authors: Ana Dolšak, Kristjan Mrgole, Matej Sova
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Catalysts
Subjects:
cross-coupling
Suzuki
palladium
pyrimidines
synthesis
microwave-assisted
Online Access:https://www.mdpi.com/2073-4344/11/4/439

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