Lactation and cardiovascular risk factors in mothers in a population-based study: the HUNT-study

<p>Abstract</p> <p>Background</p> <p>Lactation has beneficial short term effects on maternal metabolic health, but the long term effects are less well known.</p> <p>Methods</p> <p>We studied the association between lifetime duration of lactation...

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Main Authors: Natland Siv T, Nilsen Tom I L, Midthjell Kristian, Andersen Lene F, Forsmo Siri
Format: Article
Language:English
Published: BMC 2012-06-01
Series:International Breastfeeding Journal
Online Access:http://www.internationalbreastfeedingjournal.com/content/7/1/8
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spelling doaj-42cb9611011c4fce92dbe51b000b6ca72020-11-25T00:23:56ZengBMCInternational Breastfeeding Journal1746-43582012-06-0171810.1186/1746-4358-7-8Lactation and cardiovascular risk factors in mothers in a population-based study: the HUNT-studyNatland Siv TNilsen Tom I LMidthjell KristianAndersen Lene FForsmo Siri<p>Abstract</p> <p>Background</p> <p>Lactation has beneficial short term effects on maternal metabolic health, but the long term effects are less well known.</p> <p>Methods</p> <p>We studied the association between lifetime duration of lactation and cardiovascular risk factors in mothers later in life among 21,368 parous women aged 20 to 85 years attending the second Nord-Trøndelag Health Study (HUNT2) in 1995–1997, Norway, a cross-sectional population-based study. General linear modelling was used to calculate mean values of known cardiovascular risk factor levels in five categories of lifetime duration of lactation. Logistic regression was conducted to estimate odds ratios of hypertension, obesity and diabetes.</p> <p>Results</p> <p>Among women aged 50 years or younger, lifetime duration of lactation was significantly and inversely associated with body mass index (<it>P</it>-trend, < 0.001), waist circumference (<it>P</it>-trend, < 0.001), systolic and diastolic blood pressure (both <it>P</it>-trends, < 0.001), and serum levels of triglycerides, total cholesterol and low density lipoprotein cholesterol (all <it>P</it>-trends, < 0.001) after adjustment for covariates. Parous women aged 50 years or younger who had never lactated had higher prevalence of hypertension, obesity and diabetes. In this age group, compared to women who had lactated for 24 months or more, parous women who had never lactated had an OR for hypertension of 1.88 (95% CI 1.41, 2.51), an OR for obesity of 3.37 (95% CI 2.51, 4.51) and an OR for diabetes of 5.87 (95% CI 2.25, 15.3). Among women older than 50 years there were no clear associations.</p> <p>Conclusion</p> <p>Lifetime duration of lactation was associated with long term reduced cardiovascular risk levels in mothers aged 50 years or younger.</p> http://www.internationalbreastfeedingjournal.com/content/7/1/8
collection DOAJ
language English
format Article
sources DOAJ
author Natland Siv T
Nilsen Tom I L
Midthjell Kristian
Andersen Lene F
Forsmo Siri
spellingShingle Natland Siv T
Nilsen Tom I L
Midthjell Kristian
Andersen Lene F
Forsmo Siri
Lactation and cardiovascular risk factors in mothers in a population-based study: the HUNT-study
International Breastfeeding Journal
author_facet Natland Siv T
Nilsen Tom I L
Midthjell Kristian
Andersen Lene F
Forsmo Siri
author_sort Natland Siv T
title Lactation and cardiovascular risk factors in mothers in a population-based study: the HUNT-study
title_short Lactation and cardiovascular risk factors in mothers in a population-based study: the HUNT-study
title_full Lactation and cardiovascular risk factors in mothers in a population-based study: the HUNT-study
title_fullStr Lactation and cardiovascular risk factors in mothers in a population-based study: the HUNT-study
title_full_unstemmed Lactation and cardiovascular risk factors in mothers in a population-based study: the HUNT-study
title_sort lactation and cardiovascular risk factors in mothers in a population-based study: the hunt-study
publisher BMC
series International Breastfeeding Journal
issn 1746-4358
publishDate 2012-06-01
description <p>Abstract</p> <p>Background</p> <p>Lactation has beneficial short term effects on maternal metabolic health, but the long term effects are less well known.</p> <p>Methods</p> <p>We studied the association between lifetime duration of lactation and cardiovascular risk factors in mothers later in life among 21,368 parous women aged 20 to 85 years attending the second Nord-Trøndelag Health Study (HUNT2) in 1995–1997, Norway, a cross-sectional population-based study. General linear modelling was used to calculate mean values of known cardiovascular risk factor levels in five categories of lifetime duration of lactation. Logistic regression was conducted to estimate odds ratios of hypertension, obesity and diabetes.</p> <p>Results</p> <p>Among women aged 50 years or younger, lifetime duration of lactation was significantly and inversely associated with body mass index (<it>P</it>-trend, < 0.001), waist circumference (<it>P</it>-trend, < 0.001), systolic and diastolic blood pressure (both <it>P</it>-trends, < 0.001), and serum levels of triglycerides, total cholesterol and low density lipoprotein cholesterol (all <it>P</it>-trends, < 0.001) after adjustment for covariates. Parous women aged 50 years or younger who had never lactated had higher prevalence of hypertension, obesity and diabetes. In this age group, compared to women who had lactated for 24 months or more, parous women who had never lactated had an OR for hypertension of 1.88 (95% CI 1.41, 2.51), an OR for obesity of 3.37 (95% CI 2.51, 4.51) and an OR for diabetes of 5.87 (95% CI 2.25, 15.3). Among women older than 50 years there were no clear associations.</p> <p>Conclusion</p> <p>Lifetime duration of lactation was associated with long term reduced cardiovascular risk levels in mothers aged 50 years or younger.</p>
url http://www.internationalbreastfeedingjournal.com/content/7/1/8
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