Inhibition of dopamine transporter activity by G protein βγ subunits.

Uptake through the Dopamine Transporter (DAT) is the primary mechanism of terminating dopamine signaling within the brain, thus playing an essential role in neuronal homeostasis. Deregulation of DAT function has been linked to several neurological and psychiatric disorders including ADHD, schizophre...

Full description

Bibliographic Details
Main Authors: Jennie Garcia-Olivares, Delany Torres-Salazar, William A Owens, Tracy Baust, David P Siderovski, Susan G Amara, Jun Zhu, Lynette C Daws, Gonzalo E Torres
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3608556?pdf=render