Inverse Mechanistic Modeling of Transdermal Drug Delivery for Fast Identification of Optimal Model Parameters

Inverse Mechanistic Modeling of Transdermal Drug Delivery for Fast Identification of Optimal Model Parameters

Transdermal drug delivery systems are a key technology to administer drugs with a high first-pass effect in a non-invasive and controlled way. Physics-based modeling and simulation are on their way to become a cornerstone in the engineering of these healthcare devices since it provides a unique comp...

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Bibliographic Details
Main Authors: Thijs Defraeye, Flora Bahrami, René M. Rossi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Pharmacology
Subjects:
multiphysics
simulation
computational modeling of skin
finite element
pain management
therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.641111/full

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