T-regulatory cells subpopulation in bronchial asthma and heterogeneous phenotypes of chronic obstructive pulmonary disease
Aim of the study was to investigate the levels of individual subpopulations of T-regulatory (T-reg) cells in patients with different phenotypes of chronic obstructive pulmonary disease (COPD) with moderate bronchial asthma and healthy volunteers. COPD was associated with increased level of natural (...
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Siberian State Medical University (Tomsk)
2011-02-01
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| Series: | Bûlleten' Sibirskoj Mediciny |
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| Online Access: | https://bulletin.tomsk.ru/jour/article/view/1314 |
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doaj-42b28bc66af1422b933e672cb314acb22021-07-29T08:37:53ZengSiberian State Medical University (Tomsk)Bûlleten' Sibirskoj Mediciny1682-03631819-36842011-02-01101485410.20538/1682-0363-2011-1-48-54837T-regulatory cells subpopulation in bronchial asthma and heterogeneous phenotypes of chronic obstructive pulmonary diseaseN. A. Kirillova0I. A. Deyev1Ye. E. Kremer2L. M. Ogorodova3G. E. Chernogoryuk4Сибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетAim of the study was to investigate the levels of individual subpopulations of T-regulatory (T-reg) cells in patients with different phenotypes of chronic obstructive pulmonary disease (COPD) with moderate bronchial asthma and healthy volunteers. COPD was associated with increased level of natural (CD4+CD25high) T-cells, while emphysematous phenotype of disease was associated with the highest pool of natural CD4+CD25high. Bronchial asthma was associated with low levels of inducible (CD4+ FoxP3+ ) T-reg.https://bulletin.tomsk.ru/jour/article/view/1314chronic obstructive pulmonary diseasebronchial asthmacopd phenotypest-regulatory cells |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
N. A. Kirillova I. A. Deyev Ye. E. Kremer L. M. Ogorodova G. E. Chernogoryuk |
| spellingShingle |
N. A. Kirillova I. A. Deyev Ye. E. Kremer L. M. Ogorodova G. E. Chernogoryuk T-regulatory cells subpopulation in bronchial asthma and heterogeneous phenotypes of chronic obstructive pulmonary disease Bûlleten' Sibirskoj Mediciny chronic obstructive pulmonary disease bronchial asthma copd phenotypes t-regulatory cells |
| author_facet |
N. A. Kirillova I. A. Deyev Ye. E. Kremer L. M. Ogorodova G. E. Chernogoryuk |
| author_sort |
N. A. Kirillova |
| title |
T-regulatory cells subpopulation in bronchial asthma and heterogeneous phenotypes of chronic obstructive pulmonary disease |
| title_short |
T-regulatory cells subpopulation in bronchial asthma and heterogeneous phenotypes of chronic obstructive pulmonary disease |
| title_full |
T-regulatory cells subpopulation in bronchial asthma and heterogeneous phenotypes of chronic obstructive pulmonary disease |
| title_fullStr |
T-regulatory cells subpopulation in bronchial asthma and heterogeneous phenotypes of chronic obstructive pulmonary disease |
| title_full_unstemmed |
T-regulatory cells subpopulation in bronchial asthma and heterogeneous phenotypes of chronic obstructive pulmonary disease |
| title_sort |
t-regulatory cells subpopulation in bronchial asthma and heterogeneous phenotypes of chronic obstructive pulmonary disease |
| publisher |
Siberian State Medical University (Tomsk) |
| series |
Bûlleten' Sibirskoj Mediciny |
| issn |
1682-0363 1819-3684 |
| publishDate |
2011-02-01 |
| description |
Aim of the study was to investigate the levels of individual subpopulations of T-regulatory (T-reg) cells in patients with different phenotypes of chronic obstructive pulmonary disease (COPD) with moderate bronchial asthma and healthy volunteers. COPD was associated with increased level of natural (CD4+CD25high) T-cells, while emphysematous phenotype of disease was associated with the highest pool of natural CD4+CD25high. Bronchial asthma was associated with low levels of inducible (CD4+ FoxP3+ ) T-reg. |
| topic |
chronic obstructive pulmonary disease bronchial asthma copd phenotypes t-regulatory cells |
| url |
https://bulletin.tomsk.ru/jour/article/view/1314 |
| work_keys_str_mv |
AT nakirillova tregulatorycellssubpopulationinbronchialasthmaandheterogeneousphenotypesofchronicobstructivepulmonarydisease AT iadeyev tregulatorycellssubpopulationinbronchialasthmaandheterogeneousphenotypesofchronicobstructivepulmonarydisease AT yeekremer tregulatorycellssubpopulationinbronchialasthmaandheterogeneousphenotypesofchronicobstructivepulmonarydisease AT lmogorodova tregulatorycellssubpopulationinbronchialasthmaandheterogeneousphenotypesofchronicobstructivepulmonarydisease AT gechernogoryuk tregulatorycellssubpopulationinbronchialasthmaandheterogeneousphenotypesofchronicobstructivepulmonarydisease |
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1721253685800992768 |