Detection of cardiovascular calcifications: Is it a useful tool for nephrologists?

Chronic kidney disease (CKD) has been used as a model and source of knowledge concerning the mechanisms, clinical relevance and accelerated progression of cardiovascular (CV) calcification, as well as its consequences in clinical practice. However, we know that it is a late secondary ossification ph...

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Main Authors: Jordi Bover, José Luis Górriz, Pablo Ureña-Torres, María Jesús Lloret, César Ruiz-García, Iara daSilva, Pamela Chang, Mariano Rodríguez, José Ballarín
Format: Article
Language:English
Published: Elsevier 2016-11-01
Series:Nefrología (English Edition)
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2013251416301481
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spelling doaj-42a3c47c045448bbadb4e171b8e843fe2020-11-24T22:55:03ZengElsevierNefrología (English Edition)2013-25142016-11-0136658759610.1016/j.nefroe.2016.05.013Detection of cardiovascular calcifications: Is it a useful tool for nephrologists?Jordi Bover0José Luis Górriz1Pablo Ureña-Torres2María Jesús Lloret3César Ruiz-García4Iara daSilva5Pamela Chang6Mariano Rodríguez7José Ballarín8Servicio de Nefrología, Fundació Puigvert, IIB Sant Pau, RedinRen, Barcelona, SpainServicio de Nefrología, Hospital Universitario Doctor Peset, Valencia, SpainDepartamento de Nefrología y Diálisis, Clinique du Landy, Departamento de Fisiología Renal, Hospital Necker, Universidad de París Descartes, París, FranceServicio de Nefrología, Fundació Puigvert, IIB Sant Pau, RedinRen, Barcelona, SpainServicio de Nefrología, Fundació Puigvert, IIB Sant Pau, RedinRen, Barcelona, SpainServicio de Nefrología, Fundació Puigvert, IIB Sant Pau, RedinRen, Barcelona, SpainServicio de Nefrología, Fundació Puigvert, IIB Sant Pau, RedinRen, Barcelona, SpainServicio de Nefrología, Hospital de Universitario Reina Sofía, IMIBIC, Universidad de Córdoba, Córdoba, SpainServicio de Nefrología, Fundació Puigvert, IIB Sant Pau, RedinRen, Barcelona, SpainChronic kidney disease (CKD) has been used as a model and source of knowledge concerning the mechanisms, clinical relevance and accelerated progression of cardiovascular (CV) calcification, as well as its consequences in clinical practice. However, we know that it is a late secondary ossification phenomenon and only circumstantial evidence is available. In this comprehensive review, we firstly describe the types of CV calcification which affect CKD patients, and we analyse how its presence is directly associated with CV events and increased mortality in these patients. We also justify the use of CV calcification assessment in regular nephrology clinical practice, because CV calcification is an important predictor of clinical outcome in these patients. Consequently, we believe that CV calcification assessment is a tool that could and should be used by nephrologists when making a decision concerning individual patients, consistent with the current trend of an ever-more-personalised therapeutic approach.http://www.sciencedirect.com/science/article/pii/S2013251416301481Chronic kidney diseaseVascular calcificationAdragaoKauppilaAgatstonCKD-MBDMineral metabolismCalciumPhosphorusHyperparathyroidism
collection DOAJ
language English
format Article
sources DOAJ
author Jordi Bover
José Luis Górriz
Pablo Ureña-Torres
María Jesús Lloret
César Ruiz-García
Iara daSilva
Pamela Chang
Mariano Rodríguez
José Ballarín
spellingShingle Jordi Bover
José Luis Górriz
Pablo Ureña-Torres
María Jesús Lloret
César Ruiz-García
Iara daSilva
Pamela Chang
Mariano Rodríguez
José Ballarín
Detection of cardiovascular calcifications: Is it a useful tool for nephrologists?
Nefrología (English Edition)
Chronic kidney disease
Vascular calcification
Adragao
Kauppila
Agatston
CKD-MBD
Mineral metabolism
Calcium
Phosphorus
Hyperparathyroidism
author_facet Jordi Bover
José Luis Górriz
Pablo Ureña-Torres
María Jesús Lloret
César Ruiz-García
Iara daSilva
Pamela Chang
Mariano Rodríguez
José Ballarín
author_sort Jordi Bover
title Detection of cardiovascular calcifications: Is it a useful tool for nephrologists?
title_short Detection of cardiovascular calcifications: Is it a useful tool for nephrologists?
title_full Detection of cardiovascular calcifications: Is it a useful tool for nephrologists?
title_fullStr Detection of cardiovascular calcifications: Is it a useful tool for nephrologists?
title_full_unstemmed Detection of cardiovascular calcifications: Is it a useful tool for nephrologists?
title_sort detection of cardiovascular calcifications: is it a useful tool for nephrologists?
publisher Elsevier
series Nefrología (English Edition)
issn 2013-2514
publishDate 2016-11-01
description Chronic kidney disease (CKD) has been used as a model and source of knowledge concerning the mechanisms, clinical relevance and accelerated progression of cardiovascular (CV) calcification, as well as its consequences in clinical practice. However, we know that it is a late secondary ossification phenomenon and only circumstantial evidence is available. In this comprehensive review, we firstly describe the types of CV calcification which affect CKD patients, and we analyse how its presence is directly associated with CV events and increased mortality in these patients. We also justify the use of CV calcification assessment in regular nephrology clinical practice, because CV calcification is an important predictor of clinical outcome in these patients. Consequently, we believe that CV calcification assessment is a tool that could and should be used by nephrologists when making a decision concerning individual patients, consistent with the current trend of an ever-more-personalised therapeutic approach.
topic Chronic kidney disease
Vascular calcification
Adragao
Kauppila
Agatston
CKD-MBD
Mineral metabolism
Calcium
Phosphorus
Hyperparathyroidism
url http://www.sciencedirect.com/science/article/pii/S2013251416301481
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