Intrathymic laminin-mediated interactions: role in T cell migration and development

Intrathymic laminin-mediated interactions: role in T cell migration and development

Intrathymic T cell differentiation is a key process for the development and maintenance of cell-mediated immunity, and occurs concomitantly to highly regulated migratory events. We have proposed a multivectorial model for describing intrathymic thymocyte migration. One of the individual vectors comp...

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Bibliographic Details
Main Authors: Wilson eSavino, DANIELLA AREAS MENDES-DA-CRUZ, Daiane Cristina Ferreira Golbert, Ingo eRiederer, Vinicius eCotta-de-Almeida
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-11-01
Series:Frontiers in Immunology
Subjects:
Extracellular Matrix
Integrins
Thymus
thymic epithelial cells
Chemokines.
T-cell development
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00579/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00579/full

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