An information-theoretic approach to the modeling and analysis of whole-genome bisulfite sequencing data

An information-theoretic approach to the modeling and analysis of whole-genome bisulfite sequencing data

Abstract Background DNA methylation is a stable form of epigenetic memory used by cells to control gene expression. Whole genome bisulfite sequencing (WGBS) has emerged as a gold-standard experimental technique for studying DNA methylation by producing high resolution genome-wide methylation profile...

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Bibliographic Details
Main Authors: Garrett Jenkinson, Jordi Abante, Andrew P. Feinberg, John Goutsias
Format: Article
Language:English
Published: BMC 2018-03-01
Series:BMC Bioinformatics
Subjects:
DNA methylation
Genome analysis
Information theory
Ising model
Methylation analysis
WGBS data modeling and analysis
Online Access:http://link.springer.com/article/10.1186/s12859-018-2086-5

Internet

http://link.springer.com/article/10.1186/s12859-018-2086-5

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