Integrative Functional Genomics Implicated the Key T-/B-Cell Deficiency Regulator RAG1 in Transarterial Chemoembolization of Hepatocellular Carcinoma

Integrative Functional Genomics Implicated the Key T-/B-Cell Deficiency Regulator RAG1 in Transarterial Chemoembolization of Hepatocellular Carcinoma

Transarterial chemoembolization (TACE) has significantly prolonged overall survival (OS) of unresectable hepatocellular carcinoma (HCC) patients. Unfortunately, there are still a portion of patients without therapeutic responses to TACE. Although genome-wide association studies identified multiple H...

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Bibliographic Details
Main Authors: Yeyang Xu, Teng Wang, Jiajia Zeng, Bowen Wang, Liqing Zhou, Ming Yang, Li Zhang, Nasha Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
RAG1
hepatocellular carcinoma
TACE
eQTL
TCGA
genetic polymorphism
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.720791/full

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