Neutral genetic drift can alter promiscuous protein functions, potentially aiding functional evolution

<p>Abstract</p> <p>Background</p> <p>Many of the mutations accumulated by naturally evolving proteins are neutral in the sense that they do not significantly alter a protein's ability to perform its primary biological function. However, new protein functions evolve...

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Bibliographic Details
Main Authors: Lu Zhongyi, Romero Philip A, Bloom Jesse D, Arnold Frances H
Format: Article
Language:English
Published: BMC 2007-06-01
Series:Biology Direct
Online Access:http://www.biology-direct.com/content/2/1/17