Staphylococcus intermedius infections: case report and literature review

• Main Authors: Nancy Wang, Anne M. Neilan, Michael Klompas
• Format: Article
• Language: English
• Published: MDPI AG 2013-01-01
• Series: Infectious Disease Reports
• Subjects: Staphylococcus intermedius, pseudointermedius, infection, human
• Online Access: http://www.pagepress.org/journals/index.php/idr/article/view/4386

<em>Staphylococcus intermedius</em> is part of the normal skin and oral flora of dogs. Case reports of human infections are rare, but the true incidence is unknown because the pathogen is frequently misidentified as <em>Staphylococcus aureus</em>. Reported cases range from soft tissue infections to brain abscess. Most reported cases in humans have been related to dog exposure. We report a case of a 73 year old female with <em>S. intermedius</em> surgical wound infection one month following a left elbow total arthroplasty. This is the first reported human case of <em>S. intermedius</em> infection of a mechanical prosthesis. The presumed source of infection was the patient’s dog. The patient was treated with vancomycin, then switched to cefazolin and rifampin once susceptibilities were known. Case reports suggest that patients generally respond well to tailored antibiotics with complete or near-complete recovery. <em>S. intermedius</em> should be included in the differential diagnosis of invasive infection amongst patients with close contact with dogs.