Viral suppression of multiple escape mutants by de novo CD8<sup>+ </sup>T cell responses in a human immunodeficiency virus-1 Infected elite suppressor
<p>Abstract</p> <p>Elite suppressors or controllers (ES) are HIV-1 infected patients who maintain undetectable viral loads without treatment. While HLA-B*57-positive ES are usually infected with virus that is unmutated at CTL epitopes, a single, dominant variant containing CTL esca...
Main Authors: | Siliciano Robert F, Hegarty Robert W, O'Connell Karen A, Blankson Joel N |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-08-01
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Series: | Retrovirology |
Online Access: | http://www.retrovirology.com/content/8/1/63 |
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