Cyclic Mechanical Stretch Ameliorates the Degeneration of Nucleus Pulposus Cells through Promoting the ITGA2/PI3K/AKT Signaling Pathway

Cyclic Mechanical Stretch Ameliorates the Degeneration of Nucleus Pulposus Cells through Promoting the ITGA2/PI3K/AKT Signaling Pathway

Background. Intervertebral disc degeneration (IVDD) is one of the major causes of low back pain and motor deficiency. Nucleus pulposus (NP) degeneration plays a key role in the process of IVDD. The mechanical and biological interactions involved in NP degeneration have not been elucidated. The prese...

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Bibliographic Details
Main Authors:	Dandan Wang, Yuanzhen Chen, Shengnan Cao, Pengcheng Ren, Haojun Shi, Huazhong Li, Liangyu Xie, Weimin Huang, Bin Shi, Jinxiang Han
Format:	Article
Language:	English
Published:	Hindawi Limited 2021-01-01
Series:	Oxidative Medicine and Cellular Longevity
Online Access:	http://dx.doi.org/10.1155/2021/6699326

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