Wu Mei Wan attenuates CAC by regulating gut microbiota and the NF-kB/IL6-STAT3 signaling pathway

Wu Mei Wan attenuates CAC by regulating gut microbiota and the NF-kB/IL6-STAT3 signaling pathway

Background: Colorectal cancer (CRC) has a high incidence and mortality rate worldwide. Colitis-associated CRC (CAC) is used for describing the relationship between inflammation and CRC. No chemopreventive agents have been found to be both effective and safe in CRC. Therefore, the prevention and trea...

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Bibliographic Details
Main Authors: Feng Jiang, Minghao Liu, Haidan Wang, Guoping Shi, Biqing Chen, Tuo Chen, Xiaomin Yuan, Ping Zhu, Jinyong Zhou, Qiong Wang, Yugen Chen
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Colitis-associated colorectal cancer
Herb formula
Gut microbiota
NF-kB/IL-6/STAT3 pathway
Preventive drug
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220301736

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