Summary: | Objective: To compare the efficacy of selective laser trabeculoplasty (SLT) in terms of intraocular pressure (IOP)
reduction between phakic and pseudophakic patients with open-angle glaucoma (OAG).
Methods: Phakic and pseudophakic patients with OAG who had IOP ≥15 mmHg treated with ≥2 topical antiglaucoma
medications were enrolled. Pseudophakic eyes with history of complicated phacoemulsification were
excluded. SLT was performed 270 degrees by one surgeon under the same protocol. IOP was measured with
applanation preoperatively and at 1 hour, 1 week, 3 weeks and 3 months postoperatively.
Results: There were 59 eyes (38 phakia and 21 pseudophakia) from 38 patients enrolled between September 2011
and August 2012. The mean IOP significantly decreased from 19.5±2.5 and 20.2±3.2 mm Hg preoperatively to
15.6±3.4 and 15.3±3.1 mm Hg postoperatively at 3 months in phakic and pseudophakic group respectively. Mean
IOP reduction was not significantly different between phakic (3.9± 3.1 mmHg) and pseudophakic group (5.0±3.06
mmHg, p=0.197). The non-inferiority test indicated that mean IOP reduction in pseudophakic group was noninferior
to phakic group (p=0.012).
Conclusion: SLT was effective for IOP reduction in both phakic and pseudophakic eyes with OAG. The efficacy of
SLT in pseudophakic eyes was not inferior to phakic eyes.
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