Rapid fabrication of reinforced and cell-laden vascular grafts structurally inspired by human coronary arteries
Bioengineering of small diameter vascular grafts that recapitulate the features of native vessels is extremely challenging. Here the authors present a combined dip-spinning and blow-spinning technology to fabricate multi-layered cell-embedded grafts with native mechanical properties.
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| Format: | Article |
| Language: | English |
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Nature Publishing Group
2019-07-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-019-11090-3 |
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doaj-424ad244121c48faaec2b622564233152021-05-11T12:05:28ZengNature Publishing GroupNature Communications2041-17232019-07-0110111510.1038/s41467-019-11090-3Rapid fabrication of reinforced and cell-laden vascular grafts structurally inspired by human coronary arteriesTamara L. Akentjew0Claudia Terraza1Cristian Suazo2Jekaterina Maksimcuka3Camila A. Wilkens4Francisco Vargas5Gabriela Zavala6Macarena Ocaña7Javier Enrione8Claudio M. García-Herrera9Loreto M. Valenzuela10Jonny J. Blaker11Maroun Khoury12Juan Pablo Acevedo13Laboratory of Nano-Regenerative Medicine, Faculty of Medicine, Universidad de los AndesLaboratory of Nano-Regenerative Medicine, Faculty of Medicine, Universidad de los AndesLaboratory of Nano-Regenerative Medicine, Faculty of Medicine, Universidad de los AndesSchool of Materials, MSS Tower, The University of ManchesterLaboratory of Nano-Regenerative Medicine, Faculty of Medicine, Universidad de los AndesDepartamento de Cirugía Vascular y Endovascular, Pontificia Universidad Católica de ChileLaboratory of Nano-Regenerative Medicine, Faculty of Medicine, Universidad de los AndesLaboratory of Nano-Regenerative Medicine, Faculty of Medicine, Universidad de los AndesBiopolymer Research and Engineering Lab (BiopREL), School of Nutrition and Dietetics, Faculty of Medicine, Universidad de los AndesDepartmento de Ingeniería Mecánica, Universidad de Santiago de ChileDepartment of Chemical and Bioprocess Engineering, School of Engineering, Pontificia Universidad Católica de ChileBio-Active Materials Group, School of Materials, MSS Tower, The University of ManchesterLaboratory of Nano-Regenerative Medicine, Faculty of Medicine, Universidad de los AndesLaboratory of Nano-Regenerative Medicine, Faculty of Medicine, Universidad de los AndesBioengineering of small diameter vascular grafts that recapitulate the features of native vessels is extremely challenging. Here the authors present a combined dip-spinning and blow-spinning technology to fabricate multi-layered cell-embedded grafts with native mechanical properties.https://doi.org/10.1038/s41467-019-11090-3 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Tamara L. Akentjew Claudia Terraza Cristian Suazo Jekaterina Maksimcuka Camila A. Wilkens Francisco Vargas Gabriela Zavala Macarena Ocaña Javier Enrione Claudio M. García-Herrera Loreto M. Valenzuela Jonny J. Blaker Maroun Khoury Juan Pablo Acevedo |
| spellingShingle |
Tamara L. Akentjew Claudia Terraza Cristian Suazo Jekaterina Maksimcuka Camila A. Wilkens Francisco Vargas Gabriela Zavala Macarena Ocaña Javier Enrione Claudio M. García-Herrera Loreto M. Valenzuela Jonny J. Blaker Maroun Khoury Juan Pablo Acevedo Rapid fabrication of reinforced and cell-laden vascular grafts structurally inspired by human coronary arteries Nature Communications |
| author_facet |
Tamara L. Akentjew Claudia Terraza Cristian Suazo Jekaterina Maksimcuka Camila A. Wilkens Francisco Vargas Gabriela Zavala Macarena Ocaña Javier Enrione Claudio M. García-Herrera Loreto M. Valenzuela Jonny J. Blaker Maroun Khoury Juan Pablo Acevedo |
| author_sort |
Tamara L. Akentjew |
| title |
Rapid fabrication of reinforced and cell-laden vascular grafts structurally inspired by human coronary arteries |
| title_short |
Rapid fabrication of reinforced and cell-laden vascular grafts structurally inspired by human coronary arteries |
| title_full |
Rapid fabrication of reinforced and cell-laden vascular grafts structurally inspired by human coronary arteries |
| title_fullStr |
Rapid fabrication of reinforced and cell-laden vascular grafts structurally inspired by human coronary arteries |
| title_full_unstemmed |
Rapid fabrication of reinforced and cell-laden vascular grafts structurally inspired by human coronary arteries |
| title_sort |
rapid fabrication of reinforced and cell-laden vascular grafts structurally inspired by human coronary arteries |
| publisher |
Nature Publishing Group |
| series |
Nature Communications |
| issn |
2041-1723 |
| publishDate |
2019-07-01 |
| description |
Bioengineering of small diameter vascular grafts that recapitulate the features of native vessels is extremely challenging. Here the authors present a combined dip-spinning and blow-spinning technology to fabricate multi-layered cell-embedded grafts with native mechanical properties. |
| url |
https://doi.org/10.1038/s41467-019-11090-3 |
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