Aberrant Expressions and Variant Screening of SEMA3D in Indonesian Hirschsprung Patients

Aberrant Expressions and Variant Screening of SEMA3D in Indonesian Hirschsprung Patients

Background: The semaphorin 3D (SEMA3D) gene has been implicated in the pathogenesis of Hirschsprung disease (HSCR), a complex genetic disorder characterized by the loss of ganglion cells in varying lengths of gastrointestinal tract. We wished to investigate the role of SEMA3D variants, both rare and...

Full description

Bibliographic Details
Main Authors: Gunadi, Alvin Santoso Kalim, Nova Yuli Prasetyo Budi, Hamzah Muhammad Hafiq, Annisa Maharani, Maharani Febrianti, Fiko Ryantono, Dicky Yulianda, Kristy Iskandar, Joris A. Veltman
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Pediatrics
Subjects:
aberrant expression
Hirschsprung disease
Indonesia
SEMA3D
rare and common variants
Online Access:https://www.frontiersin.org/article/10.3389/fped.2020.00060/full

Internet

https://www.frontiersin.org/article/10.3389/fped.2020.00060/full

Similar Items