A cross-comparative pharmacokinetic study of Klimalanin (ingestion or sublingual intake)

Beta-alanine (Klimalanin) is generally used for the treatment and prevention of vasomotor disturbances (hot flushes) in menopausal period. This paper presents the results of a comparative analysis of the beta-alanine pharmacokinetics with a single ingestion and sublingual intake in the group of 12 v...

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Bibliographic Details
Main Authors: I S Yurghel, O A Limanova, T B Siling, I Yu Torshin, A N Gromov, A Yu Volkov, E Yu Egorova, O A Gromova
Format: Article
Language:Russian
Published: IP Berlin A.V. 2013-04-01
Series:Гинекология
Subjects:
Online Access:https://gynecology.orscience.ru/2079-5831/article/view/28197
Description
Summary:Beta-alanine (Klimalanin) is generally used for the treatment and prevention of vasomotor disturbances (hot flushes) in menopausal period. This paper presents the results of a comparative analysis of the beta-alanine pharmacokinetics with a single ingestion and sublingual intake in the group of 12 volunteers. The comparison showed that sublingual administration was characterized by a faster and more intense pharmacokinetics, and higher concentrations of active beta-alanine in the blood plasma.
ISSN:2079-5696
2079-5831