Overexpression of Cholesteryl Ester Transfer Protein Increases Macrophage-Derived Foam Cell Accumulation in Atherosclerotic Lesions of Transgenic Rabbits

Overexpression of Cholesteryl Ester Transfer Protein Increases Macrophage-Derived Foam Cell Accumulation in Atherosclerotic Lesions of Transgenic Rabbits

High levels of plasma high-density lipoprotein-cholesterol (HDL-C) are inversely associated with the risk of atherosclerosis and other cardiovascular diseases; thus, pharmacological inhibition of cholesteryl ester transfer protein (CETP) is considered to be a therapeutic method of raising HDL-C leve...

Full description

Bibliographic Details
Main Authors:	Shoucui Gao, Xiaojing Wang, Daxing Cheng, Jiayan Li, Lu Li, Linwu Ran, Sihai Zhao, Jianglin Fan, Enqi Liu
Format:	Article
Language:	English
Published:	Hindawi Limited 2017-01-01
Series:	Mediators of Inflammation
Online Access:	http://dx.doi.org/10.1155/2017/3824276

Similar Items

Corrigendum to “Overexpression of Cholesteryl Ester Transfer Protein Increases Macrophage-Derived Foam Cell Accumulation in Atherosclerotic Lesions of Transgenic Rabbits”
by: Shoucui Gao, et al.
Published: (2018-01-01)

Autocrine Human Urotensin II Enhances Macrophage-Derived Foam Cell Formation in Transgenic Rabbits
by: Sihai Zhao, et al.
Published: (2015-01-01)

Temporal and Quantitative Analysis of Atherosclerotic Lesions in Diet-Induced Hypercholesterolemic Rabbits
by: Qi Yu, et al.
Published: (2012-01-01)

Aggregated LDL and lipid dispersions induce lysosomal cholesteryl ester accumulation in macrophage foam cells
by: Evelyn E. Griffin, et al.
Published: (2005-10-01)

Triglyceride alters lysosomal cholesterol ester metabolism in cholesteryl ester-laden macrophage foam cells[S]
by: Jody C. Ullery-Ricewick, et al.
Published: (2009-10-01)

Expression and secretion of rabbit plasma cholesteryl ester transfer protein by Pichia pastoris
by: H Kotake, et al.
Published: (1996-03-01)

Overexpression of full-length cholesteryl ester transfer protein in SW872 cells reduces lipid accumulation
by: Lahoucine Izem, et al.
Published: (2015-03-01)

Mobilization of cytoplasmic CE droplets by overexpression of human macrophage cholesteryl ester hydrolase
by: Shobha Ghosh, et al.
Published: (2003-10-01)

Cholesteryl ester transfer protein expression is down-regulated in hyperinsulinemic transgenic mice
by: J.A. Berti, et al.
Published: (2003-10-01)

Use of fluorescent cholesteryl ester microemulsions in cholesteryl ester transfer protein assays
by: CL Bisgaier, et al.
Published: (1993-09-01)

Cloning and mRNA tissue distribution of rabbit cholesteryl ester transfer protein.
by: M Nagashima, et al.
Published: (1988-12-01)

Cholesteryl esterase and cholesteryl ester pools in corpus luteum
by: J.R.T. Coutts, et al.
Published: (1968-09-01)

Acyl unsaturation and cholesteryl ester miscibility in surfaces. Formation of lecithin-cholesteryl ester complexes
by: J M Smaby, et al.
Published: (1987-09-01)

Expression Systems and Species Used for Transgenic Animal Bioreactors
by: Yanli Wang, et al.
Published: (2013-01-01)

Effects of SFRP4 overexpression on the production of adipokines in transgenic mice
by: Yali Zhang, et al.
Published: (2020-01-01)

Liver-specific transgenic expression of cholesteryl ester hydrolase reduces atherosclerosis in Ldlr−/− mice[S]
by: Jinghua Bie, et al.
Published: (2014-04-01)

Cholesterol accumulation in human cornea: evidence that extracellular cholesteryl ester-rich lipid particles deposit independently of foam cells
by: P M Gaynor, et al.
Published: (1996-09-01)

Triglyceride enrichment of HDL does not alter HDL-selective cholesteryl ester clearance in rabbits
by: Shirya Rashid, et al.
Published: (2001-02-01)

Critical role of neutral cholesteryl ester hydrolase 1 in cholesteryl ester hydrolysis in murine macrophages[S]
by: Kent Sakai, et al.
Published: (2014-10-01)

Triglyceride and cholesteryl ester hydrolysis in a cell culture model of smooth muscle foam cells.
by: L K Minor, et al.
Published: (1989-02-01)

Accumulation and mobilization of triglycerides and cholesteryl esters in Leydig tumor cells.
by: DA Freeman, et al.
Published: (1992-08-01)

Hepatic overexpression of cholesteryl ester hydrolase enhances cholesterol elimination and in vivo reverse cholesterol transport
by: Bin Zhao, et al.
Published: (2008-10-01)

Role of cholesteryl ester transfer protein in selective uptake of high density lipoprotein cholesteryl esters by adipocytes
by: Gerard Vassiliou, et al.
Published: (2004-09-01)

Lecithin:cholesterol acyltransferase and cholesteryl ester transfer activity from the isolated perfused rabbit liver.
by: L De Parscau, et al.
Published: (1984-07-01)

ORGANOTIN SUBSTITUTED CHOLESTERYL ETHERS AND ESTERS
by: Buchanan, Heather J., et al.
Published: (1998-12-01)

Cholesteryl Ester Hydrolysis in Arterial Tissue
by: Pearson, J. D.
Published: (1974)

Inhibitors of neutral cholesteryl ester hydrolase.
by: EH Harrison, et al.
Published: (1990-12-01)

Plasma cholesteryl ester transfer protein
by: AR Tall
Published: (1993-08-01)

Cholesteryl oleyl and linoleyl ethers do not trace their ester counterparts in animals with plasma cholesteryl ester transfer activity.
by: S R Green, et al.
Published: (1989-09-01)

Overexpression of ABCG1 protein attenuates arteriosclerosis and endothelial dysfunction in atherosclerotic rabbits
by: Martin Ungerer, et al.
Published: (2012-06-01)

Comparative studies of three cholesteryl ester transfer proteins and their interactions with known inhibitors.
by: Ziyun Wang, et al.
Published: (2017-01-01)

Cholesteryl esters accumulate in the heart in a porcine model of ischemia and reperfusion.
by: Christina Drevinge, et al.
Published: (2013-01-01)

Cholesteryl ester transfer protein (CETP) is an important regulator to affect fatty liver in CETP transgenic mice
by: Jui-Chen, et al.
Published: (2009)

Farnesoid X receptor activation increases cholesteryl ester transfer protein expression in humans and transgenic mice
by: Thomas Gautier, et al.
Published: (2013-08-01)

Selective uptake of HDL cholesteryl esters is active in transgenic mice expressing human apolipoprotein A-I.
by: J C Khoo, et al.
Published: (1995-03-01)

Overexpression of Salusin-α Inhibits Vascular Intimal Hyperplasia in an Atherosclerotic Rabbit Model
by: Kun Qian, et al.
Published: (2018-01-01)

Transfer of cholesteryl ester into high density lipoprotein by cholesteryl ester transfer protein: effect of HDL lipid and apoprotein content.
by: D L Sparks, et al.
Published: (1989-10-01)

ACAT2 contributes cholesteryl esters to newly secreted VLDL, whereas LCAT adds cholesteryl ester to LDL in mice
by: Richard G. Lee, et al.
Published: (2005-06-01)

High-capacity selective uptake of cholesteryl ester from native LDL during macrophage foam cell formation
by: Jason M. Meyer, et al.
Published: (2012-10-01)

Antisense oligonucleotide inhibition of cholesteryl ester transfer protein enhances RCT in hyperlipidemic, CETP transgenic, LDLr-/- mice
by: Thomas A. Bell, III, et al.
Published: (2013-10-01)