Bone marrow abnormalities detected by magnetic resonance imaging as initial sign of hematologic malignancies

• Main Authors: Ida Sofie Grønningsæter, Aymen Bushra Ahmed, Nils Vetti, Silje Johansen, Øystein Bruserud, Håkon Reikvam
• Format: Article
• Language: English
• Published: MDPI AG 2018-06-01
• Series: Clinics and Practice
• Subjects: Leukemia; magnetic resonance imaging; bone marrow disease.
• Online Access: https://www.clinicsandpractice.org/index.php/cp/article/view/1061
• ISSN: 2039-7275; 2039-7283

The increasing use of radiological examination, especially magnetic resonance imaging (MRI), will probably increase the risk of unintended discovery of bone marrow abnormalities in patients where a hematologic disease would not be expected. In this paper we present four patients with different hematologic malignancies of non-plasma cell types. In all patients the MRI bone marrow abnormalities represent an initial presentation of the disease. These case reports illustrate the importance of a careful diagnostic follow-up without delay of patients with MRI bone marrow abnormalities, because such abnormalities can represent the first sign of both acute promyelocytic leukemia as well as other variants of acute leukemia.