Molecular alterations in basal cell carcinoma subtypes

Molecular alterations in basal cell carcinoma subtypes

Abstract A number of genes have been implicated in the pathogenesis of BCC in addition to the Hedgehog pathway, which is known to drive the initiation of this tumour. We performed in-depth analysis of 13 BCC-related genes (CSMD1, CSMD2, DPH3 promoter, PTCH1, SMO, GLI1, NOTCH1, NOTCH2, TP53, ITIH2, D...

Full description

Bibliographic Details
Main Authors:	Lucia Di Nardo, Cristina Pellegrini, Alessandro Di Stefani, Francesco Ricci, Barbara Fossati, Laura Del Regno, Carmine Carbone, Geny Piro, Vincenzo Corbo, Pietro Delfino, Simona De Summa, Maria Giovanna Maturo, Tea Rocco, Giampaolo Tortora, Maria Concetta Fargnoli, Ketty Peris
Format:	Article
Language:	English
Published:	Nature Publishing Group 2021-06-01
Series:	Scientific Reports
Online Access:	https://doi.org/10.1038/s41598-021-92592-3

Similar Items

Understanding the Molecular Genetics of Basal Cell Carcinoma
by: Cristina Pellegrini, et al.
Published: (2017-11-01)

Expression of IL-23/Th17-related cytokines in basal cell carcinoma and in the response to medical treatments.
by: Cristina Pellegrini, et al.
Published: (2017-01-01)

Intraductal Pancreatic Mucinous Neoplasms: A Tumor-Biology Based Approach for Risk Stratification
by: Vincenzo Nasca, et al.
Published: (2020-09-01)

Telomeres and Telomerase in Cutaneous Squamous Cell Carcinoma
by: Alessandra Ventura, et al.
Published: (2019-03-01)

Toll-Like Receptor 9 Agonists for Cancer Therapy
by: Davide Melisi, et al.
Published: (2014-08-01)

Mechanisms of resistance to chemotherapeutic and antiangiogenic drugs as novel targets for pancreatic cancer therapy
by: Anna eTamburrino, et al.
Published: (2013-04-01)

Pancreatic Cancer and Obesity: Molecular Mechanisms of Cell Transformation and Chemoresistance
by: Priscilla Cascetta, et al.
Published: (2018-10-01)

Angiopoietin-Like Proteins in Angiogenesis, Inflammation and Cancer
by: Carmine Carbone, et al.
Published: (2018-02-01)

<it>MC1R</it> variants predisposing to concomitant primary cutaneous melanoma in a monozygotic twin pair
by: Pellegrini Cristina, et al.
Published: (2012-09-01)

Revising PTEN in the Era of Immunotherapy: New Perspectives for an Old Story
by: Geny Piro, et al.
Published: (2019-10-01)

A cost&ndash;utility analysis of etanercept for the treatment of moderate-to-severe psoriasis in Italy
by: Giorgio L Colombo, et al.
Published: (2009-10-01)

Leser-Trélat sign as a rare manifestation of cutaneous melanoma
by: Niccolò Gori, et al.
Published: (2020-07-01)

PTEN in Lung Cancer: Dealing with the Problem, Building on New Knowledge and Turning the Game Around
by: Anastasios Gkountakos, et al.
Published: (2019-08-01)

Organoid-Transplant Model Systems to Study the Effects of Obesity on the Pancreatic Carcinogenesis in vivo
by: Francesca Lupo, et al.
Published: (2020-04-01)

Lung and Gut Microbiota as Potential Hidden Driver of Immunotherapy Efficacy in Lung Cancer
by: Carmine Carbone, et al.
Published: (2019-01-01)

Conjunctival Melanoma: Genetic and Epigenetic Insights of a Distinct Type of Melanoma
by: Ernesto Rossi, et al.
Published: (2019-10-01)

Systemic profile of immune factors in an elderly Italian population affected by chronic strongyloidiasis
by: Natalia Tiberti, et al.
Published: (2020-10-01)

Intra-patient Heterogeneity of BRAF and NRAS Molecular Alterations in Primary Melanoma and Metastases
by: Cristina Pellegrini, et al.
Published: (2020-01-01)

A case of disseminated perforating necrobiosis lipoidica
by: Niccolò Gori, et al.
Published: (2020-05-01)

Secukinumab: The Anti-IL-17A Biologic for the Treatment of Psoriasis
by: Maria Concetta Fargnoli
Published: (2019-09-01)

Pneumonitis from immune checkpoint inhibitors and COVID-19: current concern in cancer treatment
by: Giampaolo Tortora
Published: (2020-07-01)

Translational Research in the Era of Precision Medicine: Where We Are and Where We Will Go
by: Ruggero De Maria Marchiano, et al.
Published: (2021-03-01)

The Safety of Radiotherapy in the Treatment of Primary Cutaneous B-Cell Lymphoma: A Multidisciplinary Systematic Review
by: Alessandro Di Stefani, et al.
Published: (2020-07-01)

A circulating TH2 cytokines profile predicts survival in patients with resectable pancreatic adenocarcinoma
by: Geny Piro, et al.
Published: (2017-09-01)

Free-Aspire: A new device for the management of airways clearance in patient with ineffective cough
by: Luca Bertelli, et al.
Published: (2017-10-01)

Morphological and behavioural evolution through the Ediacaran and basal Cambrian of the Mackenzie Mountains, NW Canada
by: Carbone, Calla
Published: (2014)

Det osynliggjorda ledarskapet : Kvinnliga chefer i majoritet
by: Regnö, Klara
Published: (2013)

Oncological Frontiers in the Treatment of Malignant Pleural Mesothelioma
by: Emanuele Vita, et al.
Published: (2021-05-01)

CHECKlNG THE RANDOMNESS OF PSEUDORANDOM SEQUENCES FROM A BAYESIAN VIEWPOINT
by: Di Biase Giuseppe, et al.
Published: (1992-02-01)

CONSIDERAZIONI PROBABILISTICHE SU ALCUNE STRATEGIE NEI GIOCHI D'AZZARDO
by: Antonio Maturo, et al.
Published: (1994-02-01)

Studio analitico diun modello matematico per le strutture in muratura.
by: Giuseppe Di Biase, et al.
Published: (1990-02-01)

CONFRONTO FRA INFERENZA BAYESIANA E TEST CLASSICI PER L’ANALISI DI SUCCESSIONI DI NUMERI PSEUDOCASUALI
by: Giuseppe Di Biase, et al.
Published: (1991-02-01)

Multiple sclerosis - New treatment modalities
by: Rocco Totaro, et al.
Published: (2015-01-01)

Basal Cell Carcinoma: From Pathophysiology to Novel Therapeutic Approaches
by: Luca Fania, et al.
Published: (2020-10-01)

Nucleotide diversity and population differentiation of the Melanocortin 1 Receptor gene, <it>MC1R</it>
by: Peris Ketty, et al.
Published: (2008-04-01)

Metatypical basal cell carcinoma: a clinical review
by: Fama Umberto, et al.
Published: (2008-11-01)

Preparing for the next generation pharmacists
by: Joseph T. DiPiro
Published: (2020-06-01)

Critical autobiography: a new genre?
by: Laura Di Summa-Knoop
Published: (2017-01-01)

Hegel's Symbolic Stage: An Old Perspective on Contemporary Art
by: Laura T. Di Summa-Knoop
Published: (2013-01-01)

Naturalizing artifacts
by: Di Summa, Laura Teresa
Published: (2007)