Treatment of Experimental Brain Tumors with Trombospondin-1 Derived Peptides: an In Vivo Imaging Study

Treatment of Experimental Brain Tumors with Trombospondin-1 Derived Peptides: an In Vivo Imaging Study

Antiangiogenic and antiproliferative effects of synthetic D-reverse peptides derived from the type 1 repeats of thrombospondin (TSP1) [1,2] were studied in rodent C6 glioma and 9L gliosarcomas. To directly measure tumor size and vascular parameters, we employed in vivo magnetic resonance (MR) imagi...

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Bibliographic Details
Main Authors: A. Bogdanov, Jr., E. Marecos, H.C. Cheng, L. Chandrasekaran, H.C. Krutzsch, D.D. Roberts, R. Weissleder
Format: Article
Language:English
Published: Elsevier 1999-11-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
thrombospondin-1
magnetic resonance
imaging
peptide
anti-angiogenesis
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558699800153

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