Proprotein convertase subtilisin/kexin type 9 (PCSK9) gene is a risk factor of large-vessel atherosclerosis stroke.

Genetic variation in proprotein convertase subtilisin/kexin type 9 (PCSK9) gene has been recently identified as an important determinant of plasma LDL-cholesterol and severity of coronary heart disease. We studied whether the PCSK9 gene is linked to the risk of ischemic stroke (IS) and with the deve...

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Bibliographic Details
Main Authors: Shérine Abboud, Pekka J Karhunen, Dieter Lütjohann, Sirkka Goebeler, Teemu Luoto, Silvia Friedrichs, Terho Lehtimaki, Massimo Pandolfo, Reijo Laaksonen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2002510?pdf=render