Human Leukocyte Antigen and Systemic Sclerosis in Japanese: The Sign of the Four Independent Protective Alleles, DRB1*13:02, DRB1*14:06, DQB1*03:01, and DPB1*02:01.

Human Leukocyte Antigen and Systemic Sclerosis in Japanese: The Sign of the Four Independent Protective Alleles, DRB1*13:02, DRB1*14:06, DQB1*03:01, and DPB1*02:01.

Several studies on associations between human leukocyte antigen (HLA) allele frequencies and susceptibility to systemic sclerosis (SSc) have been reported. Anti-centromere antibodies (ACA) and anti-topoisomerase I antibodies (ATA) are found in SSc patients. Here, we sought to identify HLA alleles as...

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Main Authors: Hiroshi Furukawa, Shomi Oka, Aya Kawasaki, Kota Shimada, Shoji Sugii, Takashi Matsushita, Atsushi Hashimoto, Akiko Komiya, Naoshi Fukui, Kouji Kobayashi, Atsumu Osada, Atsushi Ihata, Yuya Kondo, Tatsuo Nagai, Keigo Setoguchi, Akiko Okamoto, Akira Okamoto, Noriyuki Chiba, Eiichi Suematsu, Hajime Kono, Masao Katayama, Shunsei Hirohata, Takayuki Sumida, Kiyoshi Migita, Minoru Hasegawa, Manabu Fujimoto, Shinichi Sato, Shouhei Nagaoka, Kazuhiko Takehara, Shigeto Tohma, Naoyuki Tsuchiya
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4846066?pdf=render

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