Generation of two NAGLU-mutated homozygous cell lines from healthy induced pluripotent stem cells using CRISPR/Cas9 to model Sanfilippo B syndrome

Generation of two NAGLU-mutated homozygous cell lines from healthy induced pluripotent stem cells using CRISPR/Cas9 to model Sanfilippo B syndrome

Bibliographic Details
Main Authors: Noelia Benetó, Monica Cozar, Laura Gort, Laura Pacheco, Lluïsa Vilageliu, Daniel Grinberg, Isaac Canals
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506119302983
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spelling doaj-41f73bb302f04b13a76e72b5fbda0a022020-11-25T00:00:42ZengElsevierStem Cell Research1873-50612020-01-0142Generation of two NAGLU-mutated homozygous cell lines from healthy induced pluripotent stem cells using CRISPR/Cas9 to model Sanfilippo B syndromeNoelia Benetó0Monica Cozar1Laura Gort2Laura Pacheco3Lluïsa Vilageliu4Daniel Grinberg5Isaac Canals6Department of Genetics, Microbiology and Statistics, Fac. Biology, University of Barcelona, CIBERER, IBUB, IRSJD, SpainDepartment of Genetics, Microbiology and Statistics, Fac. Biology, University of Barcelona, CIBERER, IBUB, IRSJD, SpainSecció d'Errors Congènits del Metabolisme -IBC, Servei de Bioquímica i Genètica Molecular, Hospital Clínic, IDIBAPS, CIBERER, Barcelona, SpainSecció d'Errors Congènits del Metabolisme -IBC, Servei de Bioquímica i Genètica Molecular, Hospital Clínic, IDIBAPS, CIBERER, Barcelona, SpainDepartment of Genetics, Microbiology and Statistics, Fac. Biology, University of Barcelona, CIBERER, IBUB, IRSJD, SpainDepartment of Genetics, Microbiology and Statistics, Fac. Biology, University of Barcelona, CIBERER, IBUB, IRSJD, Spain; Corresponding authors.Stem Cells, Aging and Neurodegeneration Group, Lund Stem Cell Center, University Hospital, Lund, Sweden; Corresponding authors.http://www.sciencedirect.com/science/article/pii/S1873506119302983
collection DOAJ
language English
format Article
sources DOAJ
author Noelia Benetó
Monica Cozar
Laura Gort
Laura Pacheco
Lluïsa Vilageliu
Daniel Grinberg
Isaac Canals
spellingShingle Noelia Benetó
Monica Cozar
Laura Gort
Laura Pacheco
Lluïsa Vilageliu
Daniel Grinberg
Isaac Canals
Generation of two NAGLU-mutated homozygous cell lines from healthy induced pluripotent stem cells using CRISPR/Cas9 to model Sanfilippo B syndrome
Stem Cell Research
author_facet Noelia Benetó
Monica Cozar
Laura Gort
Laura Pacheco
Lluïsa Vilageliu
Daniel Grinberg
Isaac Canals
author_sort Noelia Benetó
title Generation of two NAGLU-mutated homozygous cell lines from healthy induced pluripotent stem cells using CRISPR/Cas9 to model Sanfilippo B syndrome
title_short Generation of two NAGLU-mutated homozygous cell lines from healthy induced pluripotent stem cells using CRISPR/Cas9 to model Sanfilippo B syndrome
title_full Generation of two NAGLU-mutated homozygous cell lines from healthy induced pluripotent stem cells using CRISPR/Cas9 to model Sanfilippo B syndrome
title_fullStr Generation of two NAGLU-mutated homozygous cell lines from healthy induced pluripotent stem cells using CRISPR/Cas9 to model Sanfilippo B syndrome
title_full_unstemmed Generation of two NAGLU-mutated homozygous cell lines from healthy induced pluripotent stem cells using CRISPR/Cas9 to model Sanfilippo B syndrome
title_sort generation of two naglu-mutated homozygous cell lines from healthy induced pluripotent stem cells using crispr/cas9 to model sanfilippo b syndrome
publisher Elsevier
series Stem Cell Research
issn 1873-5061
publishDate 2020-01-01
url http://www.sciencedirect.com/science/article/pii/S1873506119302983
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