Zhile Capsule Exerts Antidepressant-Like Effects through Upregulation of the BDNF Signaling Pathway and Neuroprotection

Zhile Capsule Exerts Antidepressant-Like Effects through Upregulation of the BDNF Signaling Pathway and Neuroprotection

Major depressive disorder is now becoming a common disease in daily life, and most patients do not have satisfactory treatment outcomes. We herein evaluated the therapeutic effects of Zhile capsule and clarified the molecular mechanism. A rat model of chronic unpredictable mild stress-induced depres...

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Bibliographic Details
Main Authors: Jiawei Wu, Tingting Zhang, Luping Yu, Shuai Huang, Yu Yang, Suyun Yu, Jun Li, Yuzhu Cao, Zhonghong Wei, Xiaoman Li, Yuanyuan Wu, Wenxing Chen, Aiyun Wang, Yin Lu
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:International Journal of Molecular Sciences
Subjects:
major depressive disorder
chronic unpredictable mild stress
systems pharmacology
brain-derived neurotrophic factor
neuroprotection
Online Access:http://www.mdpi.com/1422-0067/20/1/195

Internet

http://www.mdpi.com/1422-0067/20/1/195

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