In Silico Analysis of Coding/Noncoding SNPs of Human RETN Gene and Characterization of Their Impact on Resistin Stability and Structure

In Silico Analysis of Coding/Noncoding SNPs of Human RETN Gene and Characterization of Their Impact on Resistin Stability and Structure

Resistin (RETN) is a gene coding for proinflammatory adipokine called resistin secreted by macrophages in humans. Single nucleotide polymorphisms (SNPs) in RETN are linked to obesity and insulin resistance in various populations. Using dbSNP, 78 nonsynonymous SNPs (nsSNPs) were retrieved and tested...

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Bibliographic Details
Main Authors: Lamiae Elkhattabi, Imane Morjane, Hicham Charoute, Soumaya Amghar, Hind Bouafi, Zouhair Elkarhat, Rachid Saile, Hassan Rouba, Abdelhamid Barakat
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Journal of Diabetes Research
Online Access:http://dx.doi.org/10.1155/2019/4951627

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