Engineered In Vitro Models of Tumor Dormancy and Reactivation

Abstract Metastatic recurrence is a major hurdle to overcome for successful control of cancer-associated death. Residual tumor cells in the primary site, or disseminated tumor cells in secondary sites, can lie in a dormant state for long time periods, years to decades, before being reactivated into...

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Bibliographic Details
Main Authors: Shantanu Pradhan, John L. Sperduto, Cindy J. Farino, John H. Slater
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Journal of Biological Engineering
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13036-018-0120-9