Systematic curation of miRBase annotation using integrated small RNA high-throughput sequencing data for C. elegans and Drosophila
MicroRNAs (miRNAs) are a class of 20 to 23 nucleotide small RNAs that regulate gene expression post-transcriptionally in animals and plants. Annotation of miRNAs by the miRBase database has largely relied on computational approaches. As a result, many miRBase entries lack experimental validation, an...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2011-05-01
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Series: | Frontiers in Genetics |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fgene.2011.00025/full |