Predicting the public health impact of a malaria transmission-blocking vaccine

Predicting the public health impact of a malaria transmission-blocking vaccine

Malaria transmission-blocking vaccines are in development, but roll-out strategies have not been assessed. Here, the authors show that transmission-blocking activity is likely to be higher in the field than in laboratory conditions, and that school-aged children are an important group to target.

Bibliographic Details
Main Authors: Joseph D. Challenger, Daniela Olivera Mesa, Dari F. Da, R. Serge Yerbanga, Thierry Lefèvre, Anna Cohuet, Thomas S. Churcher
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-21775-3
id doaj-41ceb2127e404427bfbc8cb9e56a16c5
record_format Article
spelling doaj-41ceb2127e404427bfbc8cb9e56a16c52021-03-11T11:33:37ZengNature Publishing GroupNature Communications2041-17232021-03-0112111210.1038/s41467-021-21775-3Predicting the public health impact of a malaria transmission-blocking vaccineJoseph D. Challenger0Daniela Olivera Mesa1Dari F. Da2R. Serge Yerbanga3Thierry Lefèvre4Anna Cohuet5Thomas S. Churcher6Medical Research Council Centre for Global Infections Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College LondonMedical Research Council Centre for Global Infections Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College LondonInstitut de Recherche en Sciences de la SantéInstitut de Recherche en Sciences de la SantéMIVEGEC, University of Montpellier, CNRS, IRDMIVEGEC, University of Montpellier, CNRS, IRDMedical Research Council Centre for Global Infections Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College LondonMalaria transmission-blocking vaccines are in development, but roll-out strategies have not been assessed. Here, the authors show that transmission-blocking activity is likely to be higher in the field than in laboratory conditions, and that school-aged children are an important group to target.https://doi.org/10.1038/s41467-021-21775-3
collection DOAJ
language English
format Article
sources DOAJ
author Joseph D. Challenger
Daniela Olivera Mesa
Dari F. Da
R. Serge Yerbanga
Thierry Lefèvre
Anna Cohuet
Thomas S. Churcher
spellingShingle Joseph D. Challenger
Daniela Olivera Mesa
Dari F. Da
R. Serge Yerbanga
Thierry Lefèvre
Anna Cohuet
Thomas S. Churcher
Predicting the public health impact of a malaria transmission-blocking vaccine
Nature Communications
author_facet Joseph D. Challenger
Daniela Olivera Mesa
Dari F. Da
R. Serge Yerbanga
Thierry Lefèvre
Anna Cohuet
Thomas S. Churcher
author_sort Joseph D. Challenger
title Predicting the public health impact of a malaria transmission-blocking vaccine
title_short Predicting the public health impact of a malaria transmission-blocking vaccine
title_full Predicting the public health impact of a malaria transmission-blocking vaccine
title_fullStr Predicting the public health impact of a malaria transmission-blocking vaccine
title_full_unstemmed Predicting the public health impact of a malaria transmission-blocking vaccine
title_sort predicting the public health impact of a malaria transmission-blocking vaccine
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2021-03-01
description Malaria transmission-blocking vaccines are in development, but roll-out strategies have not been assessed. Here, the authors show that transmission-blocking activity is likely to be higher in the field than in laboratory conditions, and that school-aged children are an important group to target.
url https://doi.org/10.1038/s41467-021-21775-3
work_keys_str_mv AT josephdchallenger predictingthepublichealthimpactofamalariatransmissionblockingvaccine
AT danielaoliveramesa predictingthepublichealthimpactofamalariatransmissionblockingvaccine
AT darifda predictingthepublichealthimpactofamalariatransmissionblockingvaccine
AT rsergeyerbanga predictingthepublichealthimpactofamalariatransmissionblockingvaccine
AT thierrylefevre predictingthepublichealthimpactofamalariatransmissionblockingvaccine
AT annacohuet predictingthepublichealthimpactofamalariatransmissionblockingvaccine
AT thomasschurcher predictingthepublichealthimpactofamalariatransmissionblockingvaccine
_version_ 1724225373578723328

Similar Items