Synthesis of Novel Steroid-Peptoid Hybrid Macrocycles by Multiple Multicomponent Macrocyclizations Including Bifunctional Building Blocks (MiBs)

Two new groups of cholane-peptoid hybrid macrocycles were produced by implementing novel combinations of the MiB methodology. Steroid-based hybrid macrolactams including heterocycle and aryl moieties were obtained by utilizing cholanic dicarboxylic acids and diamines in a bidirectional double Ugi-Fo...

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Bibliographic Details
Main Authors: Ludger A. Wessjohann, Daniel G. Rivera
Format: Article
Language:English
Published: MDPI AG 2007-08-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/12/8/1890/