Synthesis of a gadolinium based-macrocyclic MRI contrast agent for effective cancer diagnosis

Synthesis of a gadolinium based-macrocyclic MRI contrast agent for effective cancer diagnosis

Abstract Background Gadolinium-based contrast agents are widely used as a contrast agent for magnetic resonance imaging. Since gadolinium ions are toxic, many chelators are developed to bind gadolinium ions to prevent free gadolinium-associated disease. However, many reports indicated that linear ch...

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Bibliographic Details
Main Authors: Yohan Jeong, Kun Na
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Biomaterials Research
Subjects:
Magnetic resonance imaging
DOTA
Contrast agent
Macrocyclic chelator
Nephrogenic systemic fibrosis
Online Access:http://link.springer.com/article/10.1186/s40824-018-0127-9

Internet

http://link.springer.com/article/10.1186/s40824-018-0127-9

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