Inflammasomes as therapeutic targets in human diseases
Abstract Inflammasomes are protein complexes of the innate immune system that initiate inflammation in response to either exogenous pathogens or endogenous danger signals. Inflammasome multiprotein complexes are composed of three parts: a sensor protein, an adaptor, and pro-caspase-1. Activation of...
Main Authors: | Yangxin Li, Hui Huang, Bin Liu, Yu Zhang, Xiangbin Pan, Xi-Yong Yu, Zhenya Shen, Yao-Hua Song |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-07-01
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Series: | Signal Transduction and Targeted Therapy |
Online Access: | https://doi.org/10.1038/s41392-021-00650-z |
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