Macrophage-derived lipocalin-2 transports iron in the tumor microenvironment

Macrophage-derived lipocalin-2 transports iron in the tumor microenvironment

While the importance of iron for tumor development is widely appreciated, the exact sources of tumor-supporting iron largely remain elusive. The possibility that iron might be provided by stromal cells in the tumor microenvironment was not taken into account so far. In the present study, we show tha...

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Bibliographic Details
Main Authors: Christina Mertens, Javier Mora, Bilge Ören, Stephan Grein, Sofia Winslow, Klaus Scholich, Andreas Weigert, Per Malmström, Carina Forsare, Mårten Fernö, Tobias Schmid, Bernhard Brüne, Michaela Jung
Format: Article
Language:English
Published: Taylor & Francis Group 2018-03-01
Series:OncoImmunology
Subjects:
tam
iron
lipocalin-2
iron-trafficking
tumor microenvironment
tumor stroma
Online Access:http://dx.doi.org/10.1080/2162402X.2017.1408751

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