Combining Optical Approaches with Human Inducible Pluripotent Stem Cells in G Protein-Coupled Receptor Drug Screening and Development

Combining Optical Approaches with Human Inducible Pluripotent Stem Cells in G Protein-Coupled Receptor Drug Screening and Development

Drug discovery for G protein-coupled receptors (GPCRs) stands at an interesting juncture. Screening programs are slowly moving away from model heterologous cell systems such as human embryonic kidney (HEK) 293 cells to more relevant cellular, tissue and whole animal platforms. Investigators are now...

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Bibliographic Details
Main Authors: Kyla Bourque, Jace Jones-Tabah, Nourhen Mnasri, Ryan D. Martin, Terence E. Hébert
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Biomolecules
Subjects:
single cell approaches
drug discovery
iPSCs
stem cells
imaging
Online Access:https://www.mdpi.com/2218-273X/8/4/180

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